Sunday, April 17, 2011

Life-Giving Blood

It was Saturday around noon, and I was busy seeing patients in my AM clinic and juggling some issues from the ER. I received word from the family medicine resident that a patient had arrived who was suffering from an apparent intestinal bleed, with the source likely being in the stomach or the duodenum (the first part of the intestines after the stomach). We started him on some medicine in his IV for a suspected bleeding ulcer and admitted him to a hospital bed. The next step was to perform an upper endoscopy procedure to try to diagnose the cause and severity of the bleeding. However, before doing so, the patient would have to be hemodynamically stable. That’s a fancy way of saying that he would have to have a relatively normal blood pressure and pulse, and that he would appear to have a decent blood supply to all of his vital organs. Unfortunately our patient did not meet these criteria. His pulse was high, his blood pressure was low, and he appeared very sleepy (which was a result of not getting sufficient blood flow to his brain).

How do you “stabilize” a patient who has lost copious amounts of blood? By giving him loads of blood and IV fluid, of course! We began this process. After getting the equivalent of two 2-liter bottles of IV fluid pumped in, he had not stabilized. Simultaneously, he was receiving red blood cells as fast as we could give them (not fast—when they come from the lab they are packed into a very compressed state, and they run into the patient’s veins over a span of about 3 hours). After receiving the only three units of packed red cells that we had in our hospital, plus two units of fresh plasma, he STILL had not stabilized, and his symptoms told us that his intestines were still actively bleeding. There is a Red Cross in the next town over, but our lab informed me that there was no way to contact them during the night. Could we transfer the patient to another province? The patient elected to stay in our hospital, even though two important facts had become clear:
1) We had run out of blood
2) Our patient was bleeding to death.

Now it’s time to crunch the data a bit. These numbers are estimates, but they will give us some ideas of this patient’s condition. A human male about the size of my patient typically has approximately 5 liters of blood volume. We measure red blood cells, the part that carries the oxygen, by “the hemoglobin”.  A unit of whole blood contains about 450 milliliters of volume, and is expected to raise the hemoglobin by about 1.5 grams/deciliter. Our patient, before he started bleeding, probably had a hemoglobin value of around 14, which is normal. When he arrived at our hospital, his hemoglobin was 11. The next morning, after receiving the above-mentioned transfusions, his hemoglobin was 4. It was clear that our patient had essentially bled out his entire blood volume, and was now just hanging on for dear life with the little bit of blood that he had received from our lab upon his admission. At that point he looked worse than ever. He was as white as a ghost and barely responsive, and we still had no blood to offer him.

Now it was Sunday morning, and we began to ask everyone, “What can we do!!??” Our lab technician mentioned that if there were people present who wanted to give blood to our patient, the necessary tests could be performed to make that happen. Of course the donor would need to have blood type either O+ or O-, since our patient had O+ blood. The first person to step up and donate was one of our surgeons, Dr. Mattias Egberth. He was followed closely by one of our medical students, David Garcia. At about that time, approximately 20 of the patient’s relatives arrived to visit and to wish him well. They began to ask, “Can we donate as well?” Within just a few hours, we had rounded up SIX units of whole blood, which the patient gladly received. Now he was waking up, and for the first time since his admission, he was hemodynamically stable. We performed the endoscopy procedure and found a large ulcer in his duodenum. It was no longer bleeding! Thank you, God!

In all, we calculated that our patient had lost his entire blood supply and then some. By day number three, essentially none of his circulating blood was his own. He had received three units of packed red cells, six units of whole blood, and five units of fresh plasma, all because of donations by fourteen different people who were willing to give their own blood. The patient and his family were extremely grateful and humbled to know that he was alive through the sacrifice of fourteen other people, many of whom did not even know him.

Blood is an amazing creation of God, and it has long symbolized “sacrifice.” In Moses’ time, the blood of an animal was poured out on an altar in a petition for the forgiveness of sins. This was only a temporary, imperfect solution for man’s sin problem. But God made a perfect way, the only way, to salvation through the sacrificial blood of His perfect Son, Jesus Christ. “He personally carried our sins in his body on the cross so that we can be dead to sin and live for what is right. By his wounds you are healed.” (1 Peter 2:24, New Living Translation) We are alive today, and we can live in Heaven forever, because of the blood of Another, because of the blood of Jesus Christ.  And the power of Jesus’ blood does not stop when we pray to accept Him as our Rescuer. Instead, our sinful nature dies, and His perfect, righteous nature goes on living. In the same way that my patient received a completely new supply of circulating blood, we are continually filled with Christ’s perfection.
The patient gladly gave permission to share his picture and story on our blog.

5 comments:

  1. Dan, what a great story of your work following God's leadership and allowing others to be part of this medical handiwork. It's so fun to read and picture all this. I hope you and all the family are doing well and had a great Easter. We love you. Earnie

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  2. Thank you for sharing that Dan. What a blessing
    you and your family are.

    You are in our prayers,
    The Stufflebeams

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  3. Hi Dan and Kristina, Mike here. Keep the tales of your work coming... I enjoy what you post.
    Kathy and I had friends from church over a couple weeks ago, retired missionaries who have served in Shell, and in Mozambique. Now that I've found it on the map... makes more sense for me.
    g'day from chicago-land. Let us know if you pass through The Big Airport.
    g'nite

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  4. Thank you Dan for sharing. I loved how you tied your experience with your patience to what Christ's blood has done for us. Chad needs to see this as soon as he gets home and I'd like to share it with others as well. I love you guys! Syds

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  5. Hello Dan, I am a medical transcriptionist and came to this page in pursuit of a query I had regarding one of the transcriptions I was doing. it was dictated, "while in the ED, the patient was _____ and was given 2 units of PRBCs." The confusion was whether it should be hypotensive or hypertensive. Not only did I come to know that it should be "hypotensive" but also in the process came to learn a few more things (hemoglobin is the part that carries oxygen, a normal person has around 5 liters of blood circulating in the body etc.). I was very touched by the whole incident where one can realize how important it is to donate blood (which I thankfully do at least once a year)and the reference to the bible was also very enlightening. Thanks a lot sir.

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